Chromosome 9p21 polymorphism is associated with myocardial infarction but not with clinical outcome in Han Chinese
نویسندگان
چکیده
منابع مشابه
Chromosome 9p21 polymorphism is associated with myocardial infarction but not with clinical outcome in Han Chinese.
BACKGROUND rs1333049 polymorphism on chromosome 9p21 has been shown to affect susceptibility to coronary artery disease (CAD) in Caucasians. This study examined the association of rs1333049 with myocardial infarction (MI), angiographic severity of CAD and clinical outcome after a first acute MI in Han Chinese. METHODS rs1333049 polymorphism was genotyped in 520 patients with a first acute MI ...
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Recently, conflicting data have been reported regarding the possible contribution of the TSP-4 (thrombospondin-4) A387P polymorphism to CAD (coronary artery disease) or MI (myocardial infarction). To investigate a possible association between the A387P polymorphism and CAD or MI in the Chinese Han population, we conducted a case-controlled study including 817 patients with angiographically veri...
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BACKGROUND Chromosome 9p21 single nucleotide polymorphisms (SNPs) have been shown to be associated with coronary heart disease in multiple studies. The aim of the present study was to identify whether these SNPs are associated with recurrent myocardial infarction (MI), revascularization, or death in acute coronary syndrome (ACS) patients or in those undergoing coronary artery bypass grafting (C...
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Variants at chromosome 9p21 are associated with coronary artery disease (CAD). However, the longitudinal effects of 9p21 variants on cardiovascular mortality remain controversial and may depend on whether the patient has CAD. We tested the hypothesis that the single-nucleotide polymorphism (SNP) rs4977574 is associated longitudinally with cardiovascular death in patients without detectable coro...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine
سال: 2009
ISSN: 1437-4331,1434-6621
DOI: 10.1515/cclm.2009.215